Chemistry
https://www.sendspace.com/file/7cvunp
Answer the questions after Reading the guide.
P2A Guide: https://www.sendspace.com/file/zogwzp
*File may help you.
P2A S1 Pre-Lab Worksheet: https://www.sendspace.com/file/tsv7vd
P2A S1 Lab Report: https://www.sendspace.com/file/nvmhu3
P2A S1 Lab Data: https://www.sendspace.com/file/5ij251
Write the report in “P2A S2 Pre-Lab Worksheet” form.
Don’t use outside sources.
Answer all questions.
Note: you can download the files from “sendspace”.
Project 2A, Session 2
Pre-Lab Worksheet
All work must be very neat and organized. If your penmanship is poor, you must type all responses. If you need to organize your thoughts, please use a separate sheet of paper.
Question 1 (2 p) Sketch a plot of t90 vs. pH assuming kobs for the ASA hydrolysis steadily increases with increasing pH.
Question 2 (2 p) Sketch a plot of t90 vs. [Glycerol] ([Glycerol] is the glycerol concentration) assuming kobs for the ASA hydrolysis steadily decreases with increasing glycerol concentration.
Question 3 (4 p) Now sketch three separate plots on the same axes: t90 vs. [Glycerol] at pH = 6.0, t90 vs. [Glycerol] at pH = 7.0 and t90 vs. [Glycerol] at pH = 8.0. That is, given the above plots, what would the COMBINED effect look like? Label and be careful with your scaling. Clearly indicate where the optimum shelf life occurs.
Question 4 (2 p) ON THE RIGHT BELOW sketch a plot of t90 vs. [ASA] (the aspirin concentration). Take care in how you draw the plot, for this indicates what assumptions you are making about the relationship between ASA concentration and the hydrolysis kinetics.