Evaluation of Genetic Data

70. Evaluation of Genetic Data

 

Assignment details
You have been given a dataset containing Identifiler® genotypes from 200 individuals. Your first task is to analyse this dataset in terms of its potential usefulness as a database for individual identification purposes.
In an investigation being carried out in an Arab country, a match has been observed between a DNA profile generated from a crime scene stain and the DNA profile generated from a white Caucasian male arrested by police. The DNA profile generated is shown below:
D8S1179 8, 17
D21S11 34, 34.2
D7S820 9, 9
CSF1PO 8, 14
D3S1358 14, 14
TH01 8, 10
D13S317 9, 10
D16S539 14, 15
D2S1338 19, 19
D19S433 11, 14.2
vWA 18, 18
TPOX 10, 10
D18S51 11, 19
D5S818 8, 9
FGA 18.2, 19.2
Match probability estimates using this database have been provided for the investigation but the defence team has raised the inappropriateness of the database as an issue.Your second task is to evaluate why the defence team may have raised this issue.
You must present your results in a scientific manner (take a look at published articles) detailing every analysis carried out and discussing the results obtained.

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