peptide translocation domain

peptide translocation domain

Write a two page research proposal on the use of peptide translocation domain (PTD) for enhanced cytoplasmic delivery of one of the following proteins: hVEGF, IL-12, INF-a or endostatin for the treatment of cancer or diabetes. Select only one protein and only disease (either cancer or diabetes)
second section experiment ( how you will add TAT- PTD to one of those protein( hVEGF, IL-12, INF-a or endostatin) should have one figure only.

third section Characterization: How to measure you add TAT-PTD to protein, and how to measure that protein penetration to the cells.

Fourth section : expectation and result,

conclusion ::

also I can give some resources might help you in writing

Tat PTDā€“endostatin: A novel anti-angiogenesis protein with ocular barrier permeability via eye-drops (you can find it in google scholar)

another paper might help you in writing :
Enhanced delivery of human growth hormone across cell membrane by Tat-PTD

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