Individual Written Assignment
Directions:
The corresponding cases and citations are listed in separate documents posted on Blackboard. Please use your respective case/database/citation assignments to complete this assignment as stated in the directions for Parts 1, 2, and 3.If the incorrect case, database, and/or citation are used to complete the assignment, 10 points will be deducted from the final grade of each section that the incorrect case, database, and/or citation were used.
All material for this assignment is to be uploaded as one (1) document to Blackboard via Turnitin.
Clinical Scenario 2
You are assigned to follow a 35 year-old obese woman with newly diagnosed diabetes during your advanced internal medicine clerkship. This patient is currently taking metformin. Because you are unfamiliar with this drug, you would like to obtain the following information about it: what therapeutic class it belongs to, how it works, the recommended starting dose, and associated adverse effects. Your preceptor then asks you to find evidence that supports the use of metformin in obese patients with newly diagnosed diabetes.
Case 2
Primary author: Holman RR
Title: 10-year follow-up of intensive glucose control in type 2 diabetes
Journal: New England Journal of Medicine
Year: 2008
Volume: 359
Pages: 1577-1589
Referencing e
Tertiary Databases
Clinical Pharmacology:
Gold Standard, Inc. Monograph Name. Clinical Pharmacology [database online]. Available at:
http://www.clinicalpharmacology.com. Accessed: Month, Day, Year.
Facts and Comparisons
Monograph title. Title of Publication.Facts& Comparisons [database online]. St. Louis, MO:
Wolters Kluwer Health Inc; copyright date. Accessed [date, if known].
Micromedex
(Title). In: DRUGDEX® System (electronic version). Truven Health Analytics, Greenwood
Village, Colorado, USA. Available at:http://www.micromedexsolutions.com.ezproxy.mcphs.edu/ (cited: month/day/year)
Part 1: Tertiary Search
Directions: Type your answer for Part 1 directly into the document below question 1 (of 1). Please use 12-point font, Times New Roman, and single space the text.Refer to the Excel document for your assigned case number to complete this portion of the assignment. This section of the assignment will be evaluated using the Individual WrittenAssignment Part 1: Tertiary SearchEvaluation Form.
1. Identify, list in the form of a question, search, and answer all questions from your assigned case scenario that can best be answered using e-tertiary resources. Please use only the following electronic databases: Micromedex, Facts and Comparisons, and/or Clinical Pharmacology. Reference each answer appropriatelyusing 10th edition AMA Format. A link to the MCPHS library guide to citing electronic resources is posted on Blackboard. In addition, an e-tertiary resources citation guide is posted on Blackboard.Be sure to reference the individual monograph/document within the database rather than the entire database.
Part 2: Literature Search
Directions: Type your answers for Part 2(questions 1- 4 of 4) directly into this document below each respective question. Please use 12-point font, Times New Roman, and single space the text. Refer to the Excel document for your assigned secondary database to complete this portion of the assignment. Your search will be based upon the clinical case scenario assigned in Part 1. This section of the assignment will be evaluated using the Individual WrittenAssignment Part 2: Literature Search Evaluation Form.
1. Identify and list one clinical question from the case scenario that can best be searched for in a secondary resource. Underline the major concepts of the question that will be used for your literature search. (Hint: the major concepts of the question should reflect the PICO components of the question.)
P:
I:
C:
O:
Question:
2. Complete a column for each major concept in your search. Add additional columns as needed.
Concept 1: Concept 2: Concept 3: Concept 4:
MeSH term, Supplementary concept, or EMTREE term
Synonyms
Narrow terms
Broader terms
3. In your assigned secondary database, conduct a search to answer your clinical question. Select ONEclinical trial that you think might be relevant and appropriate to answer your clinical question. Provide the citation, in 10th edition AMA format (guide provided on Blackboard), for the clinical trial you selected. In addition, cut and paste or insert a screenshot of the abstract (be sure that this is readable).
4. In one paragraph, using complete sentences, summarize your literature search process. Include the following information: 1) database utilized 2) search dates utilized, 3) list of search terms, 4) how terms were combined, 5) limits used, 6) number of articles identified, 7) how articles were excluded from your search (e.g., excludes case reports or commentaries), and 8) how you selected your chosen article (e.g., RCT).
Part 3: Literature Summary
Directions: Type your answers for Part 3A (questions 1- 11 of 11) and Part 3B directly into this document below each respective section. Please use 12-point font, Times New Roman, and single space the text.Refer to the Excel document for your assigned literature citation to complete this portion of the assignment. This section of the assignment will be evaluated using the Individual Written Assignment Part 3: Literature Summary Evaluation Form
Part 3A:Evaluate and paraphrase the article
Additional directions:Do NOT copy and paste answers from the article. Answer questions by summarizing and properly paraphrasing components of the article in complete sentences. Answer each question in less than 4 sentences (goal of 1-2 sentences).
1. Who were the investigators in this trial?
2. What is the purpose of the study?
3. What type of study was conducted?
4. Who were the patients in the study? (consider inclusion/exclusion and baseline characteristics)
5. How were the study groups defined and created?
6. What intervention was used? Was there a titration or other alterations in intervention?
7. How long did patients receive the intervention? How long was the study/follow-up?
8. What were the outcomes (primary/secondary) and how were they measured?
9. What are the outcomes/results of this study?
10. What are the strengths and weaknesses of the study?
11. What is the clinical application of these results? How does this relate to the drug information question at hand?
Part 3B: Createliterature summary:
Additional directions:Limit your summary to ≤ 15 sentences. Reference your summary appropriatelyusing 10th edition AMA Format (guide provided on Blackboard). If you have questions about proper citation technique, please refer to the Citation Guide posted in the Course Information Section on Blackboard.
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