effects of adiponectin and insulin

Compare the effects of adiponectin and insulin on normal and diabetic (STZ) rat aorta contractions in high glucose conditions
1- overview about diabetes and types of diabetes.
2- why diabetes is important in the study?
3-Insulin and how used insulin in the treatment (mechanism of action of insulin).
4-Effect of insulin on contraction.
5-What is adiponectin?
6- why adiponectin is important as new treatment area?
7-Theoritically how would adiponectin change contraction of aorta?
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