How does Nicotine tolerance develop

outline the structure of the insulin receptor and its half life. Describe
the active and inactive forms.
Give examples of drugs that work via G-protein coupled receptors.
\Mat is a bifunctionrf “r=Vr”f
* *
ls the phosphorylated form of an enzyme the active form of that
enzyme? Explain.
Draw out the cascade that shows how adrenaline on binding to its
receptor eventually releases glucose.
what is the effect of aspartate on the cNS? \Mich receptor does
aspartate bind to?
I Describe how glutamate acts to increase free intracellular Ca2* levels. 9. Outline some types of calcium-dependent events that occur in the cell.
10. Discuss the interaction of insulin with the Tyrosine Kinase receptor.
11.\Mat is the half life of insulin? \Mat determines this?
12. outline the 3 differences below between the following receptors:
4.
5.
6.
7.
RECEPTOR
TYPE
Structural Signalling
Speed
Signal Propagation
Mechanism
G-Protein Coupled
Insulin Receptor

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