Infectious Mononucleosis
Case Scenario: Infectious Mononucleosis
A 21 year old student presents to your clinic with a 1 week history of a sore throat, stiffness and
tenderness in his neck, and extreme malaise. On examination, he was mildly pyrexial with posterior
cervical lymphadenopathy, palatal petechiae and pharyngeal inflammation without an exudate. Abdominal
examination showed mild splenomegaly. There was no evidence of a skin rash or jaundice.
The clinical diagnosis of infectious mononucleosis (‘glandular fever’) was confirmed on
investigation. His white cell count was 13 x 109 /L (Normal Range 4-10 x 109 /L) with over 50% of the
lymphocytes showing atypical morphology (‘atypical lymphocytosis’). His serum contained IgM
antibodies to Epstein-Barr viral capsid antigen (VCA), the most specific test for acute infectious
mononucleosis. Liver function tests were normal.
He was treated symptomatically and was advised to avoid sporting activity until his splenomegaly had
completely resolved and was recommended to abstain from alcohol for at least 6 months.
Assessment: ESSAY- MEDICAL FORMAT
The essay must discuss the clinical symptoms and pathogenesis of the condition in the context of the
information provided in the case study (see case below details). It must also describe in some detail
the following processes relating to the condition: • the infection process • the acute inflammatory
process and • the potential for chronic inflammation.
Essay requirements:
• Word count must be with in 1500 words +/- 10%. Word count over 1650 words will not be read or
assessed. Word count does not include in-text referencing, reference list, cover sheet or titles. •
Referencing must be according to the APA Referencing Guidelines. • A minimum of five academic
references is required, with at least one being a peer reviewed journal article. A maximum of ten
references is allowed. References can include journals, books and websites. • The essay should be
submitted in a Word document format through Blackboard. • The essay should be presented using Times
New Roman or Arial font, size 12 and double spaced. Essay Guidelines: • It is highly recommended to
submit a Turnitin report with the completed essay to demonstrate the level of originality.
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