Pathophysiology

Pathophysiology
The women preventative healthcare is a prime concern for adult women both before and after fertility regarding two organs: the cervix and the breast (mammary gland).

The diagnosis of cervical cancer requires two procedure the Pap smear and cervical biopsy.
• Identify and describe the oncological terminology of a Pap smear and cervical biopsy

Pap smear
Pap smear (Bethesda system) Neoplastic State
(dysplasia, cancer in situ, carcinoma) Pathological findings
LSIL
HSIL
Carcinoma

Cervical Biopsy
Cervical Biopsy
(WHO system) Neoplastic State
(dysplasia, cancer in situ, carcinoma) Pathological findings
CIN I
CIN II
CIN III
Invasive carcinoma

• The presence of this infectious organism greatly increases the risk of cervical cancer?
o The presence or absence of this microscopic epithelial structure determines whether a cancer is invasive or in situ?
• A Pap smear can identify whether a cervical cancer is invasive or in situ? True or False
Cancer staging is a crucial factor in the diagnosis and successful treatment of breast cancer. Distant metastases and inflammatory carcinoma (inflammation of the overlying fascia and skin) are characteristics of extremely advanced carcinoma and poor prognosis.

Breast Cancer

Identify the general characteristics of the following clinical stages of breast cancer
Stage Carcinoma in situ
or
invasive carcinoma TMN System characteristics
(Tumor, Metastasis, Node) Prognosis
(5-year survival)

I
II
III
IV

Describe the grading and staging of prostatic cancer. Be sure to discuss how these criteria influence survival rate
Grading by Gleason Score

Clinical staging

Benign prostatic hyperplasia (BPH) is non-neoplastic tissue growth that impact the surrounding area.

Identify the pathological consequences of BPH on the following organs:
Kidney and ureter
Urinary bladder:
Urethra:

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