1-Describe the toxicity of a skin toxicant of your choice under organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity?
Phototoxicitytetracyclines,
2-Describe the toxicity of a renal toxicant of your choice under organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity?
(Cadmium – proximal tubular dysfunction and injury)
3-Describe the toxicity of a cardiotoxicantof your choice under organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity?
(Antipsychotics: may alter function through autonomic effects – anticholinergic effects, negative inotropic effects and QT prolongation.)
4-Describe the toxicity of a blood toxicant of your choice under organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity.?
Toxic Effects on Clot Formation – warfarin
5-Describe the toxicity of a GI toxicant of your choice under the headings of organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity.?
Chemotherapeu1cs-Chemotherapy induced diarrhea (CID): is a common and severe side effect of colorectal cancer chemotherapy – 50 % of CRC patients taking 5FU (also for other therapies)
please follow this point.
You should write about chemicals that induces toxicity to specific organ. there are five organs which are (skin- Kidney- blood- heart and Gastrointestinal tract).
you have to consider these points:
1- which this organ susceptibility to toxicity
2- mechanisms of toxicity of chemicals
3target structures and the chemical/ biological factor that influent toxicity in the organ
4- how we can assessment of toxicity
1000 max word for each organ, so total 5000 words
I have already chosen the chemicals for each organs:
1-skin-
2-Kidney-
3-blood-
4-heart-
5-Gastrointestinal tract-
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